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Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan.

Chemical research in toxicology

Rehman T, Khan MM, Shad MA, Hussain M, Oyler BL, Goo YA, Goodlett DR.
PMID: 27657490
Chem Res Toxicol. 2016 Oct 17;29(10):1720-1728. doi: 10.1021/acs.chemrestox.6b00222. Epub 2016 Oct 06.

This study was conducted to investigate the protein adducts with pesticides in a cohort of 172 factory workers that were exposed to a mixture of pesticides. The 35 samples showing considerable variation in biochemical parameters, i.e., butyrylcholinestrase (BChE), serum...

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Rehman T, Khan MM, Shad MA, et al. Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan. Chem Res Toxicol. 2016;29(10):1720-1728doi: 10.1021/acs.chemrestox.6b00222.
Rehman, T., Khan, M. M., Shad, M. A., Hussain, M., Oyler, B. L., Goo, Y. A., & Goodlett, D. R. (2016). Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan. Chemical research in toxicology, 29(10), 1720-1728. https://doi.org/10.1021/acs.chemrestox.6b00222
Rehman, Tanzila, et al. "Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan." Chemical research in toxicology vol. 29,10 (2016): 1720-1728. doi: https://doi.org/10.1021/acs.chemrestox.6b00222
Rehman T, Khan MM, Shad MA, Hussain M, Oyler BL, Goo YA, Goodlett DR. Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan. Chem Res Toxicol. 2016 Oct 17;29(10):1720-1728. doi: 10.1021/acs.chemrestox.6b00222. Epub 2016 Oct 06. PMID: 27657490.
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Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.

Chemical research in toxicology

Aleo MD, Shah F, He K, Bonin PD, Rodrigues AD.
PMID: 28520417
Chem Res Toxicol. 2017 Jun 19;30(6):1365. doi: 10.1021/acs.chemrestox.7b00124. Epub 2017 May 18.

No abstract available.

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Aleo MD, Shah F, He K, et al. Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. Chem Res Toxicol. 2017;30(6):1365doi: 10.1021/acs.chemrestox.7b00124.
Aleo, M. D., Shah, F., He, K., Bonin, P. D., & Rodrigues, A. D. (2017). Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. Chemical research in toxicology, 30(6), 1365. https://doi.org/10.1021/acs.chemrestox.7b00124
Aleo, Michael D, et al. "Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals." Chemical research in toxicology vol. 30,6 (2017): 1365. doi: https://doi.org/10.1021/acs.chemrestox.7b00124
Aleo MD, Shah F, He K, Bonin PD, Rodrigues AD. Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. Chem Res Toxicol. 2017 Jun 19;30(6):1365. doi: 10.1021/acs.chemrestox.7b00124. Epub 2017 May 18. PMID: 28520417.
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Correction to The Multiple Biological Targets of Hops and Bioactive Compounds.

Chemical research in toxicology

Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM.
PMID: 31392882
Chem Res Toxicol. 2019 Aug 19;32(8):1732. doi: 10.1021/acs.chemrestox.9b00300. Epub 2019 Aug 08.

No abstract available.

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Bolton JL, Dunlap TL, Hajirahimkhan A, et al. Correction to The Multiple Biological Targets of Hops and Bioactive Compounds. Chem Res Toxicol. 2019;32(8):1732doi: 10.1021/acs.chemrestox.9b00300.
Bolton, J. L., Dunlap, T. L., Hajirahimkhan, A., Mbachu, O., Chen, S. N., Chadwick, L., Nikolic, D., van Breemen, R. B., Pauli, G. F., & Dietz, B. M. (2019). Correction to The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical research in toxicology, 32(8), 1732. https://doi.org/10.1021/acs.chemrestox.9b00300
Bolton, Judy L, et al. "Correction to The Multiple Biological Targets of Hops and Bioactive Compounds." Chemical research in toxicology vol. 32,8 (2019): 1732. doi: https://doi.org/10.1021/acs.chemrestox.9b00300
Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Correction to The Multiple Biological Targets of Hops and Bioactive Compounds. Chem Res Toxicol. 2019 Aug 19;32(8):1732. doi: 10.1021/acs.chemrestox.9b00300. Epub 2019 Aug 08. PMID: 31392882.
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Nanosafety Research-An Ongoing Story.

Chemical research in toxicology

Kraegeloh A.
PMID: 30449110
Chem Res Toxicol. 2018 Nov 19;31(11):1105. doi: 10.1021/acs.chemrestox.8b00325.

No abstract available.

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Kraegeloh A. Nanosafety Research-An Ongoing Story. Chem Res Toxicol. 2018;31(11):1105doi: 10.1021/acs.chemrestox.8b00325.
Kraegeloh, A. (2018). Nanosafety Research-An Ongoing Story. Chemical research in toxicology, 31(11), 1105. https://doi.org/10.1021/acs.chemrestox.8b00325
Kraegeloh, Annette. "Nanosafety Research-An Ongoing Story." Chemical research in toxicology vol. 31,11 (2018): 1105. doi: https://doi.org/10.1021/acs.chemrestox.8b00325
Kraegeloh A. Nanosafety Research-An Ongoing Story. Chem Res Toxicol. 2018 Nov 19;31(11):1105. doi: 10.1021/acs.chemrestox.8b00325. PMID: 30449110.
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Confronting Racism in Chemistry Journals.

Chemical research in toxicology

Burrows CJ, Huang J, Wang S, Kim HJ, Meyer GJ, Schanze K, Lee TR, Lutkenhaus JL, Kaplan D, Jones C, Bertozzi C, Kiessling L, Mulcahy MB, Lindsley CW, Finn MG, Blum JD, Kamat P, Choi W, Snyder S, Aldrich CC, Rowan S, Liu B, Liotta D, Weiss PS, Zhang D, Ganesh KN, Atwater HA, Gooding JJ, Allen DT, Voigt CA, Sweedler J, Schepartz A, Rotello V, Lecommandoux S, Sturla SJ, Hammes-Schiffer S, Buriak J, Steed JW, Wu H, Zimmerman J, Brooks B, Savage P, Tolman W, Hofmann TF, Brennecke JF, Holme TA, Merz KM, Scuseria G, Jorgensen W, Georg GI, Wang S, Proteau P, Yates JR, Stang P, Walker GC, Hillmyer M, Taylor LS, Odom TW, Carreira E, Rossen K, Chirik P, Miller SJ, Shea JE, McCoy A, Zanni M, Hartland G, Scholes G, Loo JA, Milne J, Tegen SB, Kulp DT, Laskin J.
PMID: 32558557
Chem Res Toxicol. 2020 Jul 20;33(7):1511-1513. doi: 10.1021/acs.chemrestox.0c00245. Epub 2020 Jun 19.

No abstract available.

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Burrows CJ, Huang J, Wang S, et al. Confronting Racism in Chemistry Journals. Chem Res Toxicol. 2020;33(7):1511-1513doi: 10.1021/acs.chemrestox.0c00245.
Burrows, C. J., Huang, J., Wang, S., Kim, H. J., Meyer, G. J., Schanze, K., Lee, T. R., Lutkenhaus, J. L., Kaplan, D., Jones, C., Bertozzi, C., Kiessling, L., Mulcahy, M. B., Lindsley, C. W., Finn, M. G., Blum, J. D., Kamat, P., Choi, W., Snyder, S., Aldrich, C. C., Rowan, S., Liu, B., Liotta, D., Weiss, P. S., Zhang, D., Ganesh, K. N., Atwater, H. A., Gooding, J. J., Allen, D. T., Voigt, C. A., Sweedler, J., Schepartz, A., Rotello, V., Lecommandoux, S., Sturla, S. J., Hammes-Schiffer, S., Buriak, J., Steed, J. W., Wu, H., Zimmerman, J., Brooks, B., Savage, P., Tolman, W., Hofmann, T. F., Brennecke, J. F., Holme, T. A., Merz, K. M., Scuseria, G., Jorgensen, W., Georg, G. I., Wang, S., Proteau, P., Yates, J. R., Stang, P., Walker, G. C., Hillmyer, M., Taylor, L. S., Odom, T. W., Carreira, E., Rossen, K., Chirik, P., Miller, S. J., Shea, J. E., McCoy, A., Zanni, M., Hartland, G., Scholes, G., Loo, J. A., Milne, J., Tegen, S. B., Kulp, D. T., & Laskin, J. (2020). Confronting Racism in Chemistry Journals. Chemical research in toxicology, 33(7), 1511-1513. https://doi.org/10.1021/acs.chemrestox.0c00245
Burrows, Cynthia J, et al. "Confronting Racism in Chemistry Journals." Chemical research in toxicology vol. 33,7 (2020): 1511-1513. doi: https://doi.org/10.1021/acs.chemrestox.0c00245
Burrows CJ, Huang J, Wang S, Kim HJ, Meyer GJ, Schanze K, Lee TR, Lutkenhaus JL, Kaplan D, Jones C, Bertozzi C, Kiessling L, Mulcahy MB, Lindsley CW, Finn MG, Blum JD, Kamat P, Choi W, Snyder S, Aldrich CC, Rowan S, Liu B, Liotta D, Weiss PS, Zhang D, Ganesh KN, Atwater HA, Gooding JJ, Allen DT, Voigt CA, Sweedler J, Schepartz A, Rotello V, Lecommandoux S, Sturla SJ, Hammes-Schiffer S, Buriak J, Steed JW, Wu H, Zimmerman J, Brooks B, Savage P, Tolman W, Hofmann TF, Brennecke JF, Holme TA, Merz KM, Scuseria G, Jorgensen W, Georg GI, Wang S, Proteau P, Yates JR, Stang P, Walker GC, Hillmyer M, Taylor LS, Odom TW, Carreira E, Rossen K, Chirik P, Miller SJ, Shea JE, McCoy A, Zanni M, Hartland G, Scholes G, Loo JA, Milne J, Tegen SB, Kulp DT, Laskin J. Confronting Racism in Chemistry Journals. Chem Res Toxicol. 2020 Jul 20;33(7):1511-1513. doi: 10.1021/acs.chemrestox.0c00245. Epub 2020 Jun 19. PMID: 32558557.
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Interdisciplinary Approaches and Expanding Scope in Chemical Toxicology.

Chemical research in toxicology

Wang Y.
PMID: 30350582
Chem Res Toxicol. 2018 Oct 15;31(10):991. doi: 10.1021/acs.chemrestox.8b00261.

No abstract available.

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Wang Y. Interdisciplinary Approaches and Expanding Scope in Chemical Toxicology. Chem Res Toxicol. 2018;31(10):991doi: 10.1021/acs.chemrestox.8b00261.
Wang, Y. (2018). Interdisciplinary Approaches and Expanding Scope in Chemical Toxicology. Chemical research in toxicology, 31(10), 991. https://doi.org/10.1021/acs.chemrestox.8b00261
Wang, Yinsheng. "Interdisciplinary Approaches and Expanding Scope in Chemical Toxicology." Chemical research in toxicology vol. 31,10 (2018): 991. doi: https://doi.org/10.1021/acs.chemrestox.8b00261
Wang Y. Interdisciplinary Approaches and Expanding Scope in Chemical Toxicology. Chem Res Toxicol. 2018 Oct 15;31(10):991. doi: 10.1021/acs.chemrestox.8b00261. PMID: 30350582.
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Nanosafety: Where Are We Now and Where Must We Go?.

Chemical research in toxicology

Krug H, Kraegeloh A.
PMID: 30983370
Chem Res Toxicol. 2019 Apr 15;32(4):535. doi: 10.1021/acs.chemrestox.9b00083.

No abstract available.

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Krug H, Kraegeloh A. Nanosafety: Where Are We Now and Where Must We Go?. Chem Res Toxicol. 2019;32(4):535doi: 10.1021/acs.chemrestox.9b00083.
Krug, H., & Kraegeloh, A. (2019). Nanosafety: Where Are We Now and Where Must We Go?. Chemical research in toxicology, 32(4), 535. https://doi.org/10.1021/acs.chemrestox.9b00083
Krug, Harald, and Kraegeloh, Annette. "Nanosafety: Where Are We Now and Where Must We Go?." Chemical research in toxicology vol. 32,4 (2019): 535. doi: https://doi.org/10.1021/acs.chemrestox.9b00083
Krug H, Kraegeloh A. Nanosafety: Where Are We Now and Where Must We Go?. Chem Res Toxicol. 2019 Apr 15;32(4):535. doi: 10.1021/acs.chemrestox.9b00083. PMID: 30983370.
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Quantitation of γ-Glutamylcysteine-Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography-Tandem Mass Spectrometry.

Chemical research in toxicology

Zhao Y, Chan W.
PMID: 34196185
Chem Res Toxicol. 2021 Jul 19;34(7):1782-1789. doi: 10.1021/acs.chemrestox.1c00113. Epub 2021 Jul 01.

Humans are constantly exposed to formaldehyde (FA) of both exogenous and endogenous sources, and FA exposure is associated with the development of many human diseases, including cancers. Marker molecules that can provide information on exposure history and amounts will...

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Zhao Y, Chan W. Quantitation of γ-Glutamylcysteine-Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography-Tandem Mass Spectrometry. Chem Res Toxicol. 2021;34(7):1782-1789doi: 10.1021/acs.chemrestox.1c00113.
Zhao, Y., & Chan, W. (2021). Quantitation of γ-Glutamylcysteine-Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography-Tandem Mass Spectrometry. Chemical research in toxicology, 34(7), 1782-1789. https://doi.org/10.1021/acs.chemrestox.1c00113
Zhao, Yao, and Chan, Wan. "Quantitation of γ-Glutamylcysteine-Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography-Tandem Mass Spectrometry." Chemical research in toxicology vol. 34,7 (2021): 1782-1789. doi: https://doi.org/10.1021/acs.chemrestox.1c00113
Zhao Y, Chan W. Quantitation of γ-Glutamylcysteine-Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography-Tandem Mass Spectrometry. Chem Res Toxicol. 2021 Jul 19;34(7):1782-1789. doi: 10.1021/acs.chemrestox.1c00113. Epub 2021 Jul 01. PMID: 34196185.
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Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease.

Chemical research in toxicology

Hernandez-Castillo C, Shuck SC.
PMID: 34851609
Chem Res Toxicol. 2021 Dec 01; doi: 10.1021/acs.chemrestox.1c00221. Epub 2021 Dec 01.

The obesity rate in the United States is 42.4% and has become a national epidemic. Obesity is a complex condition that is influenced by socioeconomic status, ethnicity, genetics, age, and diet. Increased consumption of a Western diet, one that...

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Hernandez-Castillo C, Shuck SC. Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease. Chem Res Toxicol. 2021;doi: 10.1021/acs.chemrestox.1c00221.
Hernandez-Castillo, C., & Shuck, S. C. (2021). Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease. Chemical research in toxicology, . https://doi.org/10.1021/acs.chemrestox.1c00221
Hernandez-Castillo, Carlos, and Shuck, Sarah C. "Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease." Chemical research in toxicology vol. (2021). doi: https://doi.org/10.1021/acs.chemrestox.1c00221
Hernandez-Castillo C, Shuck SC. Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease. Chem Res Toxicol. 2021 Dec 01; doi: 10.1021/acs.chemrestox.1c00221. Epub 2021 Dec 01. PMID: 34851609.
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Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M.

Chemical research in toxicology

Christov PP, Richie-Jannetta R, Kingsley PJ, Vemulapalli A, Kim K, Sulikowski GA, Rizzo CJ, Ketkar A, Eoff RL, Rouzer CA, Marnett LJ.
PMID: 34860508
Chem Res Toxicol. 2021 Dec 03; doi: 10.1021/acs.chemrestox.1c00334. Epub 2021 Dec 03.

The lipid peroxidation product malondialdehyde and the DNA peroxidation product base-propenal react with dG to generate the exocyclic adduct, M

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Christov PP, Richie-Jannetta R, Kingsley PJ, et al. Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M. Chem Res Toxicol. 2021;doi: 10.1021/acs.chemrestox.1c00334.
Christov, P. P., Richie-Jannetta, R., Kingsley, P. J., Vemulapalli, A., Kim, K., Sulikowski, G. A., Rizzo, C. J., Ketkar, A., Eoff, R. L., Rouzer, C. A., & Marnett, L. J. (2021). Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M. Chemical research in toxicology, . https://doi.org/10.1021/acs.chemrestox.1c00334
Christov, Plamen P, et al. "Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M." Chemical research in toxicology vol. (2021). doi: https://doi.org/10.1021/acs.chemrestox.1c00334
Christov PP, Richie-Jannetta R, Kingsley PJ, Vemulapalli A, Kim K, Sulikowski GA, Rizzo CJ, Ketkar A, Eoff RL, Rouzer CA, Marnett LJ. Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M. Chem Res Toxicol. 2021 Dec 03; doi: 10.1021/acs.chemrestox.1c00334. Epub 2021 Dec 03. PMID: 34860508.
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Quantification of Osimertinib and Metabolite-Protein Modification Reveals Its High Potency and Long Duration of Effects on Target Organs.

Chemical research in toxicology

Gong S, Zhuo Y, Chen S, Hu X, Fan XX, Wu JL, Li N.
PMID: 34665607
Chem Res Toxicol. 2021 Nov 15;34(11):2309-2318. doi: 10.1021/acs.chemrestox.1c00195. Epub 2021 Oct 19.

Covalent drugs are newly developed and proved to be successful therapies in past decades. However, the pharmacokinetics (PK) and pharmacodynamic (PD) studies of covalent drugs now ignore the drug and metabolite-protein modification. The low abundance of modified proteins also...

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Gong S, Zhuo Y, Chen S, et al. Quantification of Osimertinib and Metabolite-Protein Modification Reveals Its High Potency and Long Duration of Effects on Target Organs. Chem Res Toxicol. 2021;34(11):2309-2318doi: 10.1021/acs.chemrestox.1c00195.
Gong, S., Zhuo, Y., Chen, S., Hu, X., Fan, X. X., Wu, J. L., & Li, N. (2021). Quantification of Osimertinib and Metabolite-Protein Modification Reveals Its High Potency and Long Duration of Effects on Target Organs. Chemical research in toxicology, 34(11), 2309-2318. https://doi.org/10.1021/acs.chemrestox.1c00195
Gong, Shilin, et al. "Quantification of Osimertinib and Metabolite-Protein Modification Reveals Its High Potency and Long Duration of Effects on Target Organs." Chemical research in toxicology vol. 34,11 (2021): 2309-2318. doi: https://doi.org/10.1021/acs.chemrestox.1c00195
Gong S, Zhuo Y, Chen S, Hu X, Fan XX, Wu JL, Li N. Quantification of Osimertinib and Metabolite-Protein Modification Reveals Its High Potency and Long Duration of Effects on Target Organs. Chem Res Toxicol. 2021 Nov 15;34(11):2309-2318. doi: 10.1021/acs.chemrestox.1c00195. Epub 2021 Oct 19. PMID: 34665607.
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Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish.

Chemical research in toxicology

Liao XL, Chen ZF, Zou T, Lin ZC, Chen XF, Wang Y, Qi Z, Cai Z.
PMID: 34874164
Chem Res Toxicol. 2021 Dec 20;34(12):2558-2566. doi: 10.1021/acs.chemrestox.1c00326. Epub 2021 Dec 07.

As the main active ingredient for the treatment of fungal infections, climbazole (CBZ) is commonly used in a variety of personal care products. After its use, CBZ enters the receiving environment directly or indirectly through domestic sewage. Its concentration...

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Liao XL, Chen ZF, Zou T, et al. Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish. Chem Res Toxicol. 2021;34(12):2558-2566doi: 10.1021/acs.chemrestox.1c00326.
Liao, X. L., Chen, Z. F., Zou, T., Lin, Z. C., Chen, X. F., Wang, Y., Qi, Z., & Cai, Z. (2021). Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish. Chemical research in toxicology, 34(12), 2558-2566. https://doi.org/10.1021/acs.chemrestox.1c00326
Liao, Xiao-Liang, et al. "Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish." Chemical research in toxicology vol. 34,12 (2021): 2558-2566. doi: https://doi.org/10.1021/acs.chemrestox.1c00326
Liao XL, Chen ZF, Zou T, Lin ZC, Chen XF, Wang Y, Qi Z, Cai Z. Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish. Chem Res Toxicol. 2021 Dec 20;34(12):2558-2566. doi: 10.1021/acs.chemrestox.1c00326. Epub 2021 Dec 07. PMID: 34874164.
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